help us understand. >>guest: what happens is grapefruit activates an enzyme system that is responsible for breaking down the medicines in your body so the legals do not rise too high soen with you incorrect small amounts of grape truth juice you can get dangerously high levels of the drug causing the side effects if you took too much of the drug. >>shepard: should we avoid the juice in general? >>guest: no, i think grapefruit is a healthy alternative to soda. unfortunately, some people like it so much they drink too much of it. if you take a certain number of medication, especially medications on the list, you will be at higher risk for developing side effect. >>neil: why does it do this and not other citrus juices? >>guest: there are other citrus fruits that are associated with this, probably a good idea to avoid most citrus including lime, lemon and some oranges if you are taking some of the medicines on the list. if you are going to drink the beverages, just limit it to one or two a week. >>shepard: i